interferons type i การใช้

• Interferon-alpha, an interferon type I, was identified in 1957 as a protein that interfered with viral replication.
• It has been demonstrated that treatment of cells with interferon type I inhibits HIV replication and TRIM22 is strongly up-regulated by interferon treatment.
• Activation of these receptor leads to production of inflammatory cytokines as well as type I interferons ( interferon type I ) to help fighting viral infection.
• There are 3 types of IFNs : Interferon type I, Interferon type II and Interferon type III . The type II IFN, also called IFN?, is produced by specific cells of the immune system.
• The connection between Jaks and cytokine signaling was first revealed when a screen for genes involved in interferon type I ( IFN-1 ) signaling identified Tyk2 as an essential element, which is activated by an array of cytokine receptors.